期刊
CURRENT OPINION IN CELL BIOLOGY
卷 18, 期 6, 页码 730-741出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2006.10.009
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- NIAMS NIH HHS [AR2177, R01 AR042177-12, R01 AR047364-04, R01 AR047364, R01 AR042177, R01 AR047364-05, AR47364, K01 AR002177, R01 AR052397, AR052397, R01 AR042177-11] Funding Source: Medline
The development and regeneration of feathers have gained much attention recently because of progress in the following areas. First, pattern formation. The exquisite spatial arrangement provides a simple model for decoding the rules of morphogenesis. Second, stem cell biology. In every molting, a few stem cells have to rebuild the entire epithelial organ, providing much to learn on how to regenerate an organ physiologically. Third, evolution and development ('Evo-Devo'). The discovery of feathered dinosaur fossils in China prompted enthusiastic inquiries about the origin and evolution of feathers. Progress has been made in elucidating feather morphogenesis in five successive phases: macro-patterning, micro-patterning, intra-bud morphogenesis, follicle morphogenesis and regenerative cycling.
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