期刊
M S-MEDECINE SCIENCES
卷 22, 期 12, 页码 1061-1067出版社
EDP SCIENCES S A
DOI: 10.1051/medsci/200622121061
关键词
-
More than 99.9% of the sequence is identical when comparing the DNA from two individuals. The remaining 0.1% is responsible, along with other factors such as the environment, for the risk level of developing complex diseases (such as asthma, diabetes or cancer) or for the different pharmacological response to drugs. Despite the incredible advances in genomics in the past few years, identifying the variants involved remains difficult because of the prodigious amount of information to process. The recent completion of the Haplotype Map of the human genome has raised great hopes in the field as it is expected to help reduce the complexity of association studies and thus accelerate the discovery of genes associated with complex diseases. This review details the rationale behind the HapMap project, gives a summary of the results and also describes potential applications of the Hoplotype Map.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据