期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 44, 期 12, 页码 4511-4514出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00421-06
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Recently, three distinct genotypes of clinical herpes simplex virus type 1 (HSV-1) isolates were identified based on DNA sequence information and phylogenetic analysis of clinical isolates and laboratory strains. We utilized single-nucleotide polymorphism within the genes coding for glycoproteins G and I for rapid genotype classification by PCR and restriction enzyme cleavage. The method is suitable for high-scale genotyping of clinical HSV-1 isolates and for the detection of recombinants.
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