期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 6, 期 12, 页码 1299-1309出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706778993003
关键词
carbohydrates; combinatorial chemistry; carbohydrate scaffolds; mimetics
Carbohydrates have been proven as valuable scaffolds to display pharmocophores and the resulting molecules have demonstrated useful biological activity towards various targets including the somatostatin receptors (SSTR), integrins, HIV-1 protease, matrix metalloproteinases (MMP), multidrug resistance-associated protein (MRP), and as RNA binders. Carbohydrate-based compounds have also shown antibacterial and herbicidal activity.
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