期刊
MEDICAL MYCOLOGY
卷 44, 期 8, 页码 749-753出版社
INFORMA HEALTHCARE
DOI: 10.1080/13693780600967089
关键词
pulmonary nodule; osteomyelitis; voriconazole; surgery; fine needle aspirate
资金
- FIC NIH HHS [R01TW006644] Funding Source: Medline
- Intramural NIH HHS Funding Source: Medline
Infections due to Penicillium species other than P. marneffei are rare. We identified a boy with X-linked chronic granulomatous disease (X-CGD) with a pulmonary nodule and adjacent rib osteomyelitis caused by Penicillium piceum. The only sign of infection was an elevated sedimentation rate. P piceum was isolated by fine needle aspirate and from excised infected tissues. Surgical removal and one year of voriconazole treatment were very well tolerated and led to complete recovery. Microbiological, microscopic and molecular studies support the fungal diagnosis. P. piceum should be considered as a relevant pathogen immunocompromised patients.
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