期刊
AMERICAN JOURNAL OF DERMATOPATHOLOGY
卷 28, 期 5, 页码 442-445出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.dad.0000210393.82465.ad
关键词
cutaneous plasmacytoma; posttransplant lymphoproliferative disorder; plasmacytoma-like; heart transplant; EBV; immunoglobulin genes
类别
Extramedullary plasmacytomas in posuransplant patients are rarely encountered. We present the fifth case of a primary cutaneous plasmacytoma (posttransplant lymphoproliferative disorder, plasmacytoma-like) that developed in a heart transplant patient. The tumor presented as a solitary nodule of the skin 10 years after transplantation. It subsequently involved 2 other cutaneous sites and remained confined to the skin for 5 years. The neoplastic cells were Epstein-Barr virus small RNAs (EBER 1,2) positive and EBV-latent membrane protein 1 (LMP 1) negative, corresponding to type I EBV latency. The direct role of EBV in the development of the tumor remains uncertain.
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