期刊
CARBOHYDRATE RESEARCH
卷 341, 期 18, 页码 2901-2911出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2006.10.003
关键词
bacteria; gram-positive; lipoteichoic acid; synthesis; modifications
For the investigation of the minimal structural requirements for cytokine induction, Staphylococcus aureus lipoteichoic acid derivatives with two, three, four, and five glycerophosphate backbone moieties, carrying each a D-alanyl residue, were needed. Based on two different glycerophosphate building blocks and 6b-O-phosphitylated gentiobiosyl diacylglycerol the desired target molecules (compounds 1-4) could be readily obtained and provided for biological studies. (c) 2006 Elsevier Ltd. All rights reserved.
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