4.7 Article

Activity-based fluorescent reporters for monoamine oxidases in living cells

期刊

CHEMICAL COMMUNICATIONS
卷 -, 期 44, 页码 4647-4649

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ROYAL SOC CHEMISTRY
DOI: 10.1039/b713190a

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  1. NIGMS NIH HHS [GM79465, T32 GM066698] Funding Source: Medline

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Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/beta-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.

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