期刊
NATURAL PRODUCT REPORTS
卷 24, 期 2, 页码 327-357出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b515619j
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This review article provides an overview on the current state of research in the area of microtubule-stabilizing agents from natural sources, with a primary focus on the biochemistry, biology, and pharmacology associated with these compounds. A variety of natural products have been discovered over the last decade to inhibit human cancer cell proliferation through a taxol-like mechanism. These compounds represent a whole new range of structurally diverse lead structures for anticancer drug discovery.
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