期刊
SYNTHETIC COMMUNICATIONS
卷 37, 期 22-24, 页码 4253-4263出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910701575665
关键词
antibiotics; antitumor; epoxide; natural products; total synthesis
Short and efficient synthesis of rubrolide E from commercially available 4-methoxyacetophenone, employing ring-closing metathesis, Knoevenagel condensation, and Reformatsky reactions, are the key steps are described.
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