期刊
INTERNATIONAL JOURNAL OF PHARMACEUTICS
卷 328, 期 1, 页码 12-21出版社
ELSEVIER
DOI: 10.1016/j.ijpharm.2006.10.001
关键词
dissolution testing; USP; novel dosage forms; conventional dosage forms; immediate-release tablets; powders; extended-release; chewable tablets; buccal/sublingual tablets; chewing gums; soft gelatin capsules; suppositories; transdermal patches; semisolids; aerosols
The purpose of this article is to review USP and non-pharmacopcial dissolution testing methods for conventional and novel pharmaceutical dosage forms and give an insight to possible alternatives in drug dissolution study design and appropriate choices for dissolution media. For each dosage form first the USP method(s) for dissolution testing are reviewed followed by alternative methods used in research and development. (c) 2006 Elsevier B.V. All rights reserved.
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