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Current perspectives in dissolution testing of conventional and novel dosage forms

期刊

INTERNATIONAL JOURNAL OF PHARMACEUTICS
卷 328, 期 1, 页码 12-21

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ELSEVIER
DOI: 10.1016/j.ijpharm.2006.10.001

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dissolution testing; USP; novel dosage forms; conventional dosage forms; immediate-release tablets; powders; extended-release; chewable tablets; buccal/sublingual tablets; chewing gums; soft gelatin capsules; suppositories; transdermal patches; semisolids; aerosols

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The purpose of this article is to review USP and non-pharmacopcial dissolution testing methods for conventional and novel pharmaceutical dosage forms and give an insight to possible alternatives in drug dissolution study design and appropriate choices for dissolution media. For each dosage form first the USP method(s) for dissolution testing are reviewed followed by alternative methods used in research and development. (c) 2006 Elsevier B.V. All rights reserved.

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