期刊
TETRAHEDRON
卷 63, 期 5, 页码 1229-1242出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.11.048
关键词
heterocycles; cyclocondensation; multicomponent reactions; microwave-assisted organic synthesis; pyruvic acid derivatives; 5-aminopyrazoles
The reactions of 3-substituted 5-aminopyrazoles with arylidenepyruvic acids and their synthetic precursors, pyruvic acid and aromatic aldehydes, were studied. Several different reaction pathways for these cyclocondensation reactions were established depending on the reaction conditions and building block selection. The formation of pyrazolo[3,4-b]pyridine-6-carboxylic acids as major products and related compounds was discussed from the mechanistic point of view. (c) 2006 Elsevier Ltd. All rights reserved.
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