期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 129, 期 4, 页码 730-731出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja065064+
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Macromolecular crowding was found to significantly enhance the intrinsic catalytic efficiency of the enterobactin-specific isochorismate synthase by inducing structural change in the enzyme. This finding provides the first experimental evidence that macromolecular crowding directly affects protein structure and function in the absence of crowding-susceptible macromolecular association.
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