期刊
JOURNAL OF DENTAL RESEARCH
卷 86, 期 2, 页码 125-130出版社
INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R
DOI: 10.1177/154405910708600204
关键词
probiotics; Lactobacillus GG; Candida; the elderly; randomized trial; hyposalivation
Overgrowth of oral yeast is a common problem among the elderly. Probiotic bacteria are known to inhibit the growth of pathogenic microbes. We tested the hypothesis that cheese containing probiotic bacteria can reduce the prevalence of oral Candida. During this 16-week, randomized, double-blind, placebo-controlled study, 276 elderly people consumed daily 50 g of either probiotic (n = 136) or control cheese ( n = 140). The primary outcome measure was the prevalence of a high salivary yeast count (>= 10(4) cfu/mL) analyzed by the Dentocult (R) method. The prevalence decreased in the probiotic group from 30% to 21% (32% reduction), and increased in the control group from 28% to 34%. Probiotic intervention reduced the risk of high yeast counts by 75% (OR = 0.25, 95% CI 0.10-0.65, p = 0.004), and the risk of hyposalivation by 56% (OR = 0.44, 95% CI 0.19-1.01, p = 0.05). Thus, probiotic bacteria can be effective in controlling oral Candida and hyposalivation in the elderly.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据