期刊
ANGLE ORTHODONTIST
卷 82, 期 5, 页码 833-838出版社
E H ANGLE EDUCATION RESEARCH FOUNDATION, INC
DOI: 10.2319/072911-478.1
关键词
Pentraxin-3; Gingival crevicular fluid; Orthodontic tooth movement; Inflammation
资金
- Ministry of Education and Research from Romania PN CDI grant [573/2008]
Objectives: To measure the levels of pentraxin-3 (PTX-3) in gingival crevicular fluid (GCF) in orthodontic young and adult patients in the first 2 weeks after the orthodontic appliance to determine whether those changes occur during orthodontic treatment and if those values could be the expression of an inflammatory state. Materials and Methods: GCF samples were collected with paper strips from 16 orthodontic young patients and 13 orthodontic adult patients from an upper canine requiring distalization as a test tooth. A contralateral canine was used as a control tooth. The absorbed volume was eluted in 100 mu L phosphate-buffered saline (pH = 7.2). PTX-3 levels in GCF were determined using a commercial enzyme-linked immunosorbent assay kit, and the results were expressed in ng/mL. Results: The results showed an increase of GCF levels of PTX-3 from 1 hour before the orthodontic appliance to a maximum at 24 hours, followed by a decrease in both groups of adult and young patients. Conclusions: The results suggest PTX-3 involvement in periodontal orthodontic remodeling and the aseptic inflammation induced by the orthodontic forces. (Angle Orthod. 2012;82:833-838.)
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