期刊
BIOTECHNOLOGY AND BIOENGINEERING
卷 96, 期 2, 页码 203-209出版社
WILEY
DOI: 10.1002/bit.21301
关键词
biocompatibility; local delivery; systemic delivery; toxicity
资金
- NIGMS NIH HHS [GM073626] Funding Source: Medline
Particulate drug delivery systems have become important in experimental pharmaceutics and clinical medicine. The distinction is often made between micro- and nanoparticles, being particles with dimensions best described in micrometers and nanometers respectively. That size difference entails real differences at many levels, from formulation to in vivo usage. Here I will discuss those differences and provide examples of applications, for local and systemic drug delivery. I will outline a number of challenges of interest in particulate drug delivery.
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