期刊
AMERICAN JOURNAL OF SURGERY
卷 210, 期 1, 页码 129-133出版社
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjsurg.2014.08.022
关键词
Hepatocellular carcinoma; Cirrhosis; Portal hypertension; Surgery
类别
资金
- Applied Basic Research of Changzhou Bureau of Science and Technology
- Jiangsu Health International Exchange Supporting Program
BACKGROUND: To assess the effects of various operations for hepatocellular carcinoma with portal hypertension (PH). METHODS: Data regarding 78 patients with resectable liver cancer with PH were analyzed. Patients were divided into 3 groups: A (splenic artery ligation), B (in situ splenectomy), and C (in situ splenectomy + pericardial devascularization). RESULTS: White blood cell and platelet counts in the 3 groups increased significantly after surgery. Postoperative portal pressure was not significantly lower than preoperative portal pressure in Group A, while it was significantly lower in B. In Group C, the portal pressure after splenectomy was significantly lower than that before the operation, but not again after pericardial devascularization. The 1-, 2-, and 3-year survival rates of all the patients were 89.7%, 64.1%, and 46.1%, respectively. CONCLUSIONS: PH is not an absolute contraindication to liver resection in Child-Pugh class B cirrhotic patients. The combined surgery for hepatocellular carcinoma patients with PH is a safe choice. (C) 2015 Elsevier Inc. All rights reserved.
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