期刊
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
卷 44, 期 12, 页码 1547-1557出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.ijom.2015.04.006
关键词
osteoradionecrosis of the mandible (ORNM); clinical classification; staging system
资金
- National Natural Science Foundation of China [NSFC: 81271112]
- Development Foundation of Shanghai Municipal Human Resources and Social Security Bureau [201312]
- SMC Rising Star (A) Scholar of Shanghai Jiao Tong University
Osteoradionecrosis of the jaw is a common radiation-induced complication that may. be observed in oral cancer patients. Several classifications and staging systems have been proposed for osteoradionecrosis of the mandible based on clinical symptoms, radiological findings, and/or the response to diverse treatments. However, none has been universally accepted because of their individual deficiencies. The aim of this study was to introduce a new clinical classification that can be applied to the treatment of osteoradionecrosis in an easier and more acceptable way, through a retrospective analysis of patients with osteoradionecrosis of the mandible. A review was conducted of 99 patients diagnosed with osteoradionecrosis of the mandible in the study institution between 2000 and 2013. A novel classification was established on the basis of bone necrosis and soft tissue defects. A new staging system with four different stages (stage 0, stage I, stage II, and stage III) is proposed. We believe that this new classification and staging system is easier and more acceptable for clinical evaluation than previous ones.
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