期刊
CANCER RESEARCH
卷 67, 期 3, 页码 847-850出版社
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/0008-5472.CAN-06-3468
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- NCI NIH HHS [R01CA108854, P01 CA26731, R01CA67529] Funding Source: Medline
- NCRR NIH HHS [T32RR07036] Funding Source: Medline
- NIAID NIH HHS [R01 AI50952] Funding Source: Medline
- NIEHS NIH HHS [P30 ES002109, P30 ES02109] Funding Source: Medline
Anti-inflammatory drugs and antibiotics alter the risk of breast cancer in women, but roles for bacteria and inflammation in breast malignancies are poorly understood. A recent study in mice suggests that intestinal bacteria can trigger mammary carcinoma. The mechanisms involved in this effect suggest that dysregulated host immune responses to enteric bacteria can influence the development of extraintestinal cancers, highlighting the opportunities for prevention and treatment aimed at promoting intestinal homeostasis.
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