期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 57, 期 43, 页码 14235-14239出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201809376
关键词
alkynes; cyclizations; gold; homogenous catalysis; synthetic methods
资金
- Australian Research Council [DP160101682]
A synthetic method to prepare bicyclo[6.3.0]undeca-2,4,9,trienyl esters efficiently from gold(I)-catalyzed Rautenstrauch rearrangement/1,5-hydride shift/8-endo-dig cyclization of 1-ene-4,10-diynyl esters is described. The suggested double cycloisomerization mechanism delineates the first example of an unactivated all-carbon tethered 1,7-enyne, either preformed or formed in situ, which undergoes an 8-endo-dig cyclization pathway to give a cyclooctane motif. It also offers an extremely rare synthetic method in organic chemistry that can sequentially assemble both ring components of the bicyclic motif from an acyclic precursor in one step.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据