期刊
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
卷 297, 期 1, 页码 27-36出版社
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.ijmm.2006.10.003
关键词
type III secretion; T3SS; ATPase; chaperone; proton motive force
Type III secretion systems (T3SSs) are engaged by a broad number of Gram-negative bacteria to inject proteins into host cells. The simultaneous crossing of three biological membranes by these proteins is a phenomenon which is far from being understood mechanistically. However, recent work from several groups has substantially enriched our conception of how proteins travel from the bacterial into the host cell cytosol. Here, we focus on the role of specific T3SS chaperones, the specific ATPase, and the proton motive force in type III secretion. (c) 2006 Elsevier GmbH. All rights reserved.
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