A novel approach to magnetic nanoadsorbents with high binding capacity for bovine serum albumin

Magnetic nanoadsorbents using Fe(3)O(4) nanoparticles as cores and poly(methyl acrylic acid) (PAAAA) as ionic exchange groups were prepared through our novel approach. Two steps were involved in this approach: the first was to functionalize the magnetic nanoparticles (MNPs) with methacrylate double bonds via the combination of ligand exchange and condensation of methacryloxypropyltrimethoxysilane(MPS); the second was to graft PMAA chains onto the surface of MNPs through radical polymerization. The success of the various surface functionalization steps was ascertained using FTIR and XPS. The as-synthesized PMAAcoated MNPs were effective in binding bovine serum albumin (BSA) with a high capacity of 1300 mg center dot g(-1).