期刊
TETRAHEDRON
卷 63, 期 7, 页码 1706-1714出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.10.070
关键词
beta-cyclodextrin; diaza-crown ether; pseudo-cryptand; Busulfan; inclusion; molecular modelling
The synthesis of a C-2-symmetric receptor including two beta-cyclodextrins connected by urea linkers to a chiral diaza-crown ether organising platform is reported. This molecular system, long thought to be a potent selective carrier for chiral/achiral organic/inorganic guests at the supramolecular level, was found to be an efficient complexing tool towards the Busulfan anticancer agent. (c) 2006 Published by Elsevier Ltd.
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