Direct reductive amination and selective 1,2-reduction of α,β-unsaturated aldehydes and ketones by NaBH4 using H3PW12O40 as catalyst

A simple and convenient procedure for direct reductive amination of aldehydes and ketones with sodium borohydride is described. The reaction has been carried out in methanol in the presence of a catalytic amount of H3PW12O40 (0.5 mol %). alpha,beta-unsaturated aldehydes and ketones can be easily converted into the corresponding allyl alcohols by reaction with H3PW12O40 (0.5 mol %)/NaBH4. (c) 2006 Elsevier Ltd. All rights reserved.