期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 53, 期 16, 页码 4181-4185出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201310056
关键词
catalysis; fluorine; palladium; regioselectivity; stereospecificity
资金
- European Union [PIEF-GA-2011-300774, FP7-PEOPLE-2012-ITN-RADIOMI-316882]
- Royal Society Wolfson Research Merit Award
This paper describes the hydrofluorination of alkenes through sequential H- and F+ addition under palladium catalysis. The reaction is cisspecific, thus providing access to benzylic fluorides. The mechanism of this reaction involves an ionic pathway and is distinct from known hydrofluorinations involving radical intermediates. The first catalytic enantioselective hydrofluorination is also disclosed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据