4.8 Article

Conformational control of transmembrane Cl- transport

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 129, 期 7, 页码 1886-+

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AMER CHEMICAL SOC
DOI: 10.1021/ja068067v

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  1. Engineering and Physical Sciences Research Council [EP/D03549X/1] Funding Source: researchfish
  2. EPSRC [EP/D03549X/1] Funding Source: UKRI

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Preorganization of the isophthalamide cleft in N,N'-dibutyl-4,6-dihydroxyisophthalamide (2) by means of intramolecular hydrogen bonds results in an enhanced anion receptor that displays significant chloride transport activity into EYPC liposomes. This function is easily switchable by controlling the pH.

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