A novel multivalent nanomaterial based hydrogen peroxide sensor

Most of the H2O2 biosensors developed till date are based on enzymes and proteins causing them to have a limited lifetime. Moreover, complex procedures are followed for sensor fabrication. Therefore an inorganic material based sensor, with a simple design and longer shelf-life is highly desirable. In this work, an electrochemical microsensor has been designed, fabricated and tested for hydrogen peroxide detection. The 3-5 run, nonagglomerated cerium oxide particles were synthesized and integrated with the microsensor. This greatly increases the sensor lifetime, sensitivity and robustness. The sensor is characterized and tested using samples from I mu M to 30 mM H2O2 range and a linear response is observed. Miniaturization, low detection limits, high sensitivity as well as ease of fabrication are some of the advantages of this work. Same principle could be extended for the detection of other free radicals as well. (c) 2006 Elsevier B.V. All rights reserved.