期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 22, 期 3, 页码 347-356出版社
WILEY
DOI: 10.1359/JBMR.061117
关键词
osteoblasts; androgen receptor; Cre/loxP; bone; type 1a1 collagen promoter
The mechanism of androgen action on bone was studied in male mice with the AR deleted in mature osteoblasts. These mice had decreased trabecular bone volume associated with a decrease in trabecular number, suggesting that androgens may act directly on osteoblasts to maintain trabecular bone.
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