期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 190, 期 -, 页码 255-259出版社
ROYAL COLLEGE OF PSYCHIATRISTS
DOI: 10.1192/bjp.bp.106.020768
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- Medical Research Council [G9815508] Funding Source: researchfish
- Medical Research Council [G9815508] Funding Source: Medline
- Wellcome Trust Funding Source: Medline
Background Low birth weight, prematurity and higher miscarriage rates have previously been reported in women with eating disorders. Aims To determine whether women with a history of eating disorders are at higher risk of major adverse perinatal outcomes. Methods Adjusted birth weight, preterm delivery and miscarriage history were compared in those with a history of eating disorders (anorexia nervosa (n=171), bulimia nervosa (n=199) and both (n=82)) and those with other (n=1 166) and no psychiatric disorders (n=10 636) in a longitudinal cohort study. Results The group with bulimia nervosa had significantly higher rates of past miscarriages (relative risk ratio 2.0, P=0.01) and the group with anorexia nervosa delivered babies of significantly lower birth weight than the general population (P=0.01), which was mainly explained by lower pre-pregnancy body mass index. Preterm delivery rates were comparable across groups. Conclusions Women with a history of eating disorders are at higher risk of major adverse obstetric outcomes. Antenatal services should be aware of this higher risk. Declaration of interest None. Funding detailed in Acknowledgements.
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