期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 52, 期 26, 页码 6580-6589出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201209145
关键词
colloids; drug delivery; nanomedicine; nanoparticles; soft lithography
资金
- Liquidia Technologies
- Carolina Center for Cancer Nanotechnology Excellence [U54A151652]
- University Cancer Research Fund
- NIH [IDP10D006432, R01 (R01EB009565)]
- National Science Foundation [DMR-0923604, DMR-0906985]
- NATIONAL CANCER INSTITUTE [U54CA151652] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB009565] Funding Source: NIH RePORTER
- OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH [DP1OD006432] Funding Source: NIH RePORTER
Particle replication in nonwetting templates (PRINT) is a continuous, roll-to-roll, high-resolution molding technology which allows the design and synthesis of precisely defined micro- and nanoparticles. This technology adapts the lithographic techniques from the microelectronics industry and marries these with the roll-to-roll processes from the photographic film industry to enable researchers to have unprecedented control over particle size, shape, chemical composition, cargo, modulus, and surface properties. In addition, PRINT is a GMP-compliant (GMP=good manufacturing practice) platform amenable for particle fabrication on a large scale. Herein, we describe some of our most recent work involving the PRINT technology for application in the biomedical and material sciences.
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