相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Configurational Assignment of Secondary Hydroxyl Groups and Methyl Branches in Polyketide Natural Products through Bioinformatic Analysis of the Ketoreductase Domain
Andreas Kitsche et al.
CHEMBIOCHEM (2013)
Pellasoren: Structure Elucidation, Biosynthesis, and Total Synthesis of a Cytotoxic Secondary Metabolite from Sorangium cellulosum
Christine Jahns et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Full Stereochemical Determination of Ajudazols A and B by Bioinformatics Gene Cluster Analysis and Total Synthesis of Ajudazol B by an Asymmetric Ortholithiation Strategy
Sebastian Essig et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite
Katja M. Fisch et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
Raul Perez-Jimenez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Asymmetric Total Synthesis of Soraphen A: A Flexible Alkyne Strategy
Barry M. Trost et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Evolution of metabolic diversity: Insights from microbial polyketide synthases
Holger Jenke-Kodama et al.
PHYTOCHEMISTRY (2009)
Prediction and Manipulation of the Stereochemistry of Enoylreduction in Modular Polyketide Synthases
David H. Kwan et al.
CHEMISTRY & BIOLOGY (2008)
Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum
Dirk Menche et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Chemical inhibition of Acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
Annelies Beckers et al.
CANCER RESEARCH (2007)
Competitive cationic pathways and the asymmetric synthesis of aryl-substituted cyclopropanes
Bruce J. Melancon et al.
ORGANIC LETTERS (2007)
Chivosazole A - Elucidation of the absolute and relative configuration
Dominic Janssen et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of glycolate units into ansamitocin and soraphen A
Silke C. Wenzel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Studies toward soraphen A: An aldol-metathesis avenue to the macrocyclic framework
Guillaume Vincent et al.
ORGANIC LETTERS (2006)
The structure of a ketoreductase determines the organization of the β-carbon processing enzymes of modular polyketide synthases
AT Keatinge-Clay et al.
STRUCTURE (2006)
Evolutionary implications of bacterial polyketide synthases
H Jenke-Kodama et al.
MOLECULAR BIOLOGY AND EVOLUTION (2005)
Enzymatic resolution of 1,1-dimethoxybut-3-en-2-ol and 1,1-dimethoxypent-4-en-2-ol, α-hydroxyaldehyde precursors for aldol-type reactions
R Chênevert et al.
TETRAHEDRON-ASYMMETRY (2005)
Resurrecting ancestral alcohol dehydrogenases from yeast
JM Thomson et al.
NATURE GENETICS (2005)
An effective use of benzoic anhydride and its derivatives for the synthesis of carboxylic esters and lactones: A powerful and convenient mixed anhydride method promoted by basic catalysts
I Shiina et al.
JOURNAL OF ORGANIC CHEMISTRY (2004)
A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme a carboxylase by soraphen A, a macrocyclic polyketide natural product
Y Shen et al.
MOLECULAR CELL (2004)
Expression and characterization of recombinant fungal acetyl-CoA carboxylase and isolation of a soraphen-binding domain
SC Weatherly et al.
BIOCHEMICAL JOURNAL (2004)
Myxobacteria:: proficient producers of novel natural products with various biological activities -: past and future biotechnological aspects with the focus on the genus Sorangium
K Gerth et al.
JOURNAL OF BIOTECHNOLOGY (2003)
Cell-cycle-dependent three-dimensional redistribution of nuclear proteins, P 120, pKi-67, and SC 35 splicing factor, in the presence of the topoisomerase I inhibitor camptothecin
E Elias et al.
EXPERIMENTAL CELL RESEARCH (2003)
Resurrecting the ancestral steroid receptor: Ancient origin of estrogen signaling
JW Thornton et al.
SCIENCE (2003)
Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins
EA Gaucher et al.
NATURE (2003)
The direct and enantioselective organocatalytic α-oxidation of aldehydes
SP Brown et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketicle synthases
P Caffrey
CHEMBIOCHEM (2003)
A model of structure and catalysis for ketoreductase domains in modular polyketide synthases
R Reid et al.
BIOCHEMISTRY (2003)
A facile and rapid route to highly enantiopure 1,2-diols by novel catalytic asymmetric alpha-aminoxylation of aldehydes
GF Zhong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Recent developments in olefin cross-metathesis
SJ Connon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Enantioselective synthesis of 2-deoxy- and 2,3-dideoxyhexoses
MH Haukaas et al.
ORGANIC LETTERS (2002)
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26
J Ligon et al.
GENE (2002)
A practical synthesis of (+)-discodermolide and analogues: Fragment union by complex aldol reactions
I Paterson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)