In vitro activities of tigecycline and eight other antimicrobials against different Nocardia species identified by molecular methods

The in vitro activities of tigecycline and other antimicrobials against 51 isolates of Nocardia spp. were evaluated. MIC,os and MIC ranges were as follows: tigecycline, 4 and <= 0.06 to 8 mg/liter, respectively; minocycline, 2 and <= 0.06 to 2 mg/liter, respectively; linezolid, 1 and <= 0.06 to 2 mg/liter, respectively; moxifloxacin, 2 and <= 0.06 to > 64 mg/liter, respectively; ertapenem, 32 and <= 0.06-> 64 mg/liter, respectively; imipenem, 2 and <= 0.06 to > 64 mg/liter, respectively; meropenem, 8 and <= 0.06 to > 64 mg/liter, respectively; amikacin, 1 and <= 0.06 to 32 mg/liter, respectively; and trimethoprim-sulfamethoxazole, 1/19 and <= 0.5/9.5 to > 2/38 mg/liter, respectively.