期刊
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
卷 31, 期 2, 页码 81-90出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compmedimag.2006.11.001
关键词
magnetic resonance imaging; brain; intensity nonuniformity; correction
A novel approach for correcting intensity nonuniformity in magnetic resonance imaging (MRI) is presented. This approach is based on the simultaneous use of spatial and gray-level histogram information. Spatial information about intensity nonuniformity is obtained using cubic B-spline smoothing. Gray-level histogram information of the image corrupted by intensity nonuniformity is exploited from a frequential. point of view. The proposed correction method is illustrated using both physical phantom and human brain images. The results are consistent with theoretical prediction, and demonstrate a new way of dealing with intensity nonuniformity problems. They are all the more significant as the ground truth on intensity nonuniformity is unknown in clinical images. (c) 2006 Published by Elsevier Ltd.
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