期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 9, 期 2, 页码 159-164出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020500480423
关键词
metabolites; mangrove endophytic fungus; Penicillium thomi; 4 ',5-dihydroxy-2,3-dimethoxy-4-(hydroxypropyl)-biphenyl; cytotoxic effect
The chemical constituents research of the fermentation of Penicillium thomi separated from the root of Bruguiera gymnorrhiza led to the isolation of a new compound, 4',5-dihydroxy-2,3-dimethoxy-4(hydroxypropyl)-biphenyl (11) and 11 known compounds. The structures of isolated compounds were determined by spectroscopic and chemical analysis. Their cytotoxic effects against three human cancer cell lines (A549, HepG2 and HT29) were also investigated.
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