期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 51, 期 21, 页码 5062-5085出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201107017
关键词
C?C coupling; cross-coupling; homogeneous catalysis; Nobel Prize 2010; palladium
资金
- Johnson Matthey Catalysis & Chiral Technologies
In 2010, Richard Heck, Ei-ichi Negishi, and Akira Suzuki joined the prestigious circle of Nobel Laureate chemists for their roles in discovering and developing highly practical methodologies for C?C bond construction. From their original contributions in the early 1970s the landscape of the strategies and methods of organic synthesis irreversibly changed for the modern chemist, both in academia and in industry. In this Review, we attempt to trace the historical origin of these powerful reactions, and outline the developments from the seminal discoveries leading to their eminent position as appreciated and applied today.
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