4.8 Review

CurcuminuFrom Molecule to Biological Function

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Determination of curcuminoid colouring principles in commercial foods by HPLC

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Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach

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Chemopreventive effect of dietary curcumin on inflammation-induced colorectal carcinogenesis in mice

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Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis

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Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

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Return to homeostasis: downregulation of NF-κB responses

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Curcumin Attenuates Aluminum-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain

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PHARMACEUTICAL RESEARCH (2011)

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Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts

Insa M. A. Ernst et al.

PHARMACOLOGICAL RESEARCH (2011)

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Curcumin Protects against NMDA-Induced Toxicity: A Possible Role for NR2A Subunit

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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

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Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

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JOURNAL OF APPLIED PHYSIOLOGY (2010)

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Curcumin Decreases Amyloid-β Peptide Levels by Attenuating the Maturation of Amyloid-β Precursor Protein

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Curcumin Improves Outcomes and Attenuates Focal Cerebral Ischemic Injury via Antiapoptotic Mechanisms in Rats

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NEUROCHEMICAL RESEARCH (2010)

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Histone deacetylases and epigenetic therapies of hematological malignancies

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PHARMACOLOGICAL RESEARCH (2010)

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ACTA PHARMACOLOGICA SINICA (2009)

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Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies

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BIOORGANIC & MEDICINAL CHEMISTRY (2009)

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Curcumin is a potent DNA hypomethylation agent

Zhongfa Liu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

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Curcumin blocks brain tumor formation

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BRAIN RESEARCH (2009)

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Blinded by the Light: The Growing Complexity of p53

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Surveillance of the quality of turmeric powders from city markets of India on the basis of curcumin content and the presence of extraneous colours

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γ-Tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice

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INTERNATIONAL JOURNAL OF CANCER (2009)

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Evaluation of an Oral Carrier System in Rats: Bioavailability and Antioxidant Properties of Liposome-Encapsulated Curcumin

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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)

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Curcuminoid Biosynthesis by Two Type III Polyketide Synthases in the Herb Curcuma longa

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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Histone Deacetylase Inhibitors: Potential in Cancer Therapy

P. A. Marks et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Review Oncology

Histone Deacetylase Inhibitors in Cancer Therapy

Andrew A. Lane et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

Review Cell Biology

Many roads to maturity: microRNA biogenesis pathways and their regulation

Julia Winter et al.

NATURE CELL BIOLOGY (2009)

Review Pharmacology & Pharmacy

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

Bharat B. Aggarwal et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Article Biochemistry & Molecular Biology

Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2

Koremu K. Meja et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials

Alexios S. Strimpakos et al.

ANTIOXIDANTS & REDOX SIGNALING (2008)

Editorial Material Pharmacology & Pharmacy

Curcumin as Curecumin:: From kitchen to clinic

Ajay Goel et al.

BIOCHEMICAL PHARMACOLOGY (2008)

Review Pharmacology & Pharmacy

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

Preetha Anand et al.

BIOCHEMICAL PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

The biosynthetic pathway of curcuminoid in turmeric (Curcuma longa) as revealed by 13C-labeled precursors

Tomoko Kita et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)

Article Oncology

Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects

Shaiju K. Vareed et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)

Article Biochemistry & Molecular Biology

Antioxidant and radical scavenging properties of curcumin

Tuba Ak et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2008)

Article Clinical Neurology

Potential role of curcumin in stroke prevention

Bruce Ovbiagele

Expert Review of Neurotherapeutics (2008)

Article Biochemistry & Molecular Biology

Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain

Manisha Rastogi et al.

FREE RADICAL RESEARCH (2008)

Letter Pharmacology & Pharmacy

Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease

Larry Baum et al.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2008)

Article Pharmacology & Pharmacy

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

Aynun N. Begum et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Biochemistry & Molecular Biology

Anti-ischemic effect of curcumin in rat brain

Pradeep K. Shukla et al.

NEUROCHEMICAL RESEARCH (2008)

Article Chemistry, Multidisciplinary

Murine Prostate Cancer Inhibition by Dietary Phytochemicals-Curcumin and Phenyethylisothiocyanate

Avantika Barve et al.

PHARMACEUTICAL RESEARCH (2008)

Article Cell Biology

Anti cancer effects of curcumin: cycle of life and death

Gaurisankar Sa et al.

Cell Division (2008)

Article Integrative & Complementary Medicine

Recent advances in the investigation of curcuminoids

Hideji Itokawa et al.

Chinese Medicine (2008)

Article Respiratory System

Review: Antioxidant therapeutic advances in COPD

Irfan Rahman

Therapeutic Advances in Respiratory Disease (2008)

Review Immunology

New regulators of NF-κB in inflammation

Sankar Ghosh et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Review Medicine, Research & Experimental

Bioavailability of curcumin: Problems and promises

Preetha Anand et al.

MOLECULAR PHARMACEUTICS (2007)

Article Chemistry, Multidisciplinary

Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia

Cheng-yun Jin et al.

ACTA PHARMACOLOGICA SINICA (2007)

Review Biochemistry & Molecular Biology

Histone deacetylase inhibitors: molecular mechanisms of action

W. S. Xu et al.

ONCOGENE (2007)

Article Food Science & Technology

Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases

Simone I. Hoehle et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2007)

Article Pharmacology & Pharmacy

Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase

Yi Yang et al.

BIOCHEMICAL PHARMACOLOGY (2007)

Article Oncology

Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine

Timothy H. Marczylo et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2007)

Article Biochemical Research Methods

Oral bioavailabilit of curcurnin in rat and the herbal analysis from Curcuma longa by LC-MS/MS

Kuo-Yi Yang et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)

Article Pharmacology & Pharmacy

Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage

Jun Jiang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

Article Pharmacology & Pharmacy

Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats

Kuntal Maiti et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Plant Sciences

NMR study of the solution structure of curcumin

Florastina Payton et al.

JOURNAL OF NATURAL PRODUCTS (2007)

Article Multidisciplinary Sciences

MicroRNA-155 is induced during the macrophage inflammatory response

Ryan M. O'Connell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Genetics & Heredity

Cancer epigenomics: DNA methylomes and histone-modification maps

Manel Esteller

NATURE REVIEWS GENETICS (2007)

Article Biochemistry & Molecular Biology

Distinct mechanisms underlie distinct polyphenol-induced neuroprotection

Keiko Yazawa et al.

FEBS LETTERS (2006)

Article Multidisciplinary Sciences

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

Konstantin D. Taganov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Cell Biology

Control of translation and mRNA degradation by miRNAs and siRNAs

MA Valencia-Sanchez et al.

GENES & DEVELOPMENT (2006)

Article Chemistry, Medicinal

Curcumin is an Inhibitor of p300 Histone Acetylatransferase

Monica G. Marcu et al.

MEDICINAL CHEMISTRY (2006)

Article Chemistry, Applied

Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin

GK Jayaprakasha et al.

FOOD CHEMISTRY (2006)

Article Oncology

Curcumin content of turmeric and curry powders

Reema R. Tayyem et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2006)

Review Biotechnology & Applied Microbiology

Epigenetic therapy of cancer: past, present and future

CB Yoo et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Biotechnology & Applied Microbiology

Anticancer activities of histone deacetylase inhibitors

Jessica E. Bolden et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Biochemistry & Molecular Biology

Histone modifying enzymes and cancer: Going beyond histones

K Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Synthesis and biological evaluation of polyhydroxycurcuminoids

S Venkateswarlu et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Anti-oxidant activities of curcumin and related enones

WM Weber et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2005)

Article Pharmacology & Pharmacy

Curcumin-induced histone hypoacetylation: The role of reactive oxygen species

JH Kang et al.

BIOCHEMICAL PHARMACOLOGY (2005)

Article Biochemistry & Molecular Biology

Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo

FS Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Chemistry, Multidisciplinary

Epigenetics - An epicenter of gene regulation: Histones and histone-modifying enzymes

M Biel et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)

Article Biochemistry & Molecular Biology

Curcumin blocks NF-κB and the motogenic response in Helicobacter pylori-infected epithelial cells

A Foryst-Ludwig et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Spectroscopy

Determination of acidity constants of curcumin in aqueous solution and apparent rate constant of its decomposition

M Bernabé-Pineda et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2004)

Article Multidisciplinary Sciences

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

JH Suh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

N Wakabayashi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Intrinsic tumour suppression

SW Lowe et al.

NATURE (2004)

Article Chemistry, Medicinal

Synthesis of curcumin analogues as potential antioxidant, cancer chemopreventive agents

KM Youssef et al.

ARCHIV DER PHARMAZIE (2004)

Review Multidisciplinary Sciences

Epigenetics in human disease and prospects for epigenetic therapy

G Egger et al.

NATURE (2004)

Article Biochemistry & Molecular Biology

Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts

A Hayashi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Review Oncology

Cancer chemoprevention with dietary phytochemicals

YJ Surh

NATURE REVIEWS CANCER (2003)

Article Biochemistry & Molecular Biology

Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin

KI Priyadarsini et al.

FREE RADICAL BIOLOGY AND MEDICINE (2003)

Article Biochemistry & Molecular Biology

Curcurnin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

E Balogun et al.

BIOCHEMICAL JOURNAL (2003)

Article Chemistry, Medicinal

Interplay between MRP inhibition and metabolism of MRP inhibitors: The case of curcumin

HM Wortelboer et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2003)

Article Pharmacology & Pharmacy

Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain

AI Ghoneim et al.

PHARMACOLOGICAL RESEARCH (2002)

Article Biochemistry & Molecular Biology

Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of γ-glutamylcysteine synthetase

KR Sekhar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2002)

Article Agriculture, Multidisciplinary

Study on the supramolecular interaction of curcumin and β-cyclodextrin by spectrophotometry and its analytical application

B Tang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction

T Choudhuri et al.

FEBS LETTERS (2002)

Article Biochemistry & Molecular Biology

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

A Mukhopadhyay et al.

ONCOGENE (2001)

Article Geriatrics & Gerontology

Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology

SA Frautschy et al.

NEUROBIOLOGY OF AGING (2001)

Article Nutrition & Dietetics

Molecular aspects of lipoic acid in the prevention of diabetes complications

L Packer et al.

NUTRITION (2001)

Review Biotechnology & Applied Microbiology

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals:: down-regulation of COX-2 and iNOS through suppression of NF-κB activation

YJ Surh et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2001)

Review Neurosciences

Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

R Sattler et al.

MOLECULAR NEUROBIOLOGY (2001)

Article Chemistry, Multidisciplinary

How curcumin works preferentially with water soluble antioxidants

SV Jovanovic et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)

Review Plant Sciences

Review on some plants of Indian traditional medicine with antioxidant activity

P Scartezzini et al.

JOURNAL OF ETHNOPHARMACOLOGY (2000)