期刊
CLINICAL LYMPHOMA & MYELOMA
卷 7, 期 5, 页码 376-378出版社
CIG MEDIA GROUP, LP
DOI: 10.3816/CLM.2007.n.017
关键词
bone involvement; computed tomography; magnetic resonance imaging; neuroradiology
类别
Intracranial multiple myeloma is uncommon. Cavernous sinus involvement has rarely been reported, generally associated with treatment-refractory disease and poor outcome. We report clinical data and neuroradiologic findings of 3 patients with multiple myeloma and unilateral cavernous sinus involvement. At neuroradiology, this resulted from diffuse bone involvement as disease relapse (n = 2) or focal dural disease (n = 1) as the presenting sign. Interestingly, bortezomib treatment resulted in complete clinical resolution in 1 patient and partial clinical and significant magnetic resonance response in another, whereas in the literature, local radiation therapy has been reported as the only efficient treatment.
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