相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Interplay between Mutasynthesis and Semisynthesis: Generation and Evaluation of an Ansamitocin Library
Simone Eichner et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Combined Muta- and Semisynthesis: A Powerful Synthetic Hybrid Approach to Access Target Specific Antitumor Agents Based on Ansamitocin P3
Florian Taft et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
Assessing Oxazole Bioisosteres as Mutasynthons on the Rhizoxin Assembly Line
Bjoern Kusebauch et al.
CHEMBIOCHEM (2011)
Ten key issues in modern flow chemistry
Jens Wegner et al.
CHEMICAL COMMUNICATIONS (2011)
Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
Jagath R. Junutula et al.
CLINICAL CANCER RESEARCH (2010)
Frontiers and Opportunities in Chemoenzymatic Synthesis
Jonathan D. Mortison et al.
JOURNAL OF ORGANIC CHEMISTRY (2010)
Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms
Kento Koketsu et al.
NATURE CHEMICAL BIOLOGY (2010)
Biocatalytic asymmetric formation of tetrahydro-β-carbolines
Peter Bernhardt et al.
TETRAHEDRON LETTERS (2010)
New, Highly Active Nonbenzoquinone Geldanamycin Derivatives by Using Mutasynthesis
Simone Eichner et al.
CHEMBIOCHEM (2009)
Aza-Tryptamine Substrates in Monoterpene Indole Alkaloid Biosynthesis
Hyang-Yeol Lee et al.
CHEMISTRY & BIOLOGY (2009)
Opportunities for enzyme engineering in natural product biosynthesis
Peter Bernhardt et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Bypassing stereoselectivity in the early steps of alkaloid biosynthesis
Peter Bernhardt et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
Synthesis and biochemical evaluation of des-vinyl secologanin aglycones with alternate stereochemistry
Peter Bernhardt et al.
TETRAHEDRON LETTERS (2009)
Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome
Alessandra S. Eustaquio et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis
Nancy Yerkes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Highly active ansamitocin derivatives:: Mutasynthesis using an AHBA-Blocked mutant
Florian Taft et al.
CHEMBIOCHEM (2008)
The chemistry and biology of the maytansinoid antitumor agents
Andreas Kirschning et al.
COMPTES RENDUS CHIMIE (2008)
Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity
Yousong Ding et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Characterization of the β-methylaspartate-α-decarboxylase (CrpG) from the cryptophycin Biosynthetic pathway
Zachary Q. Beck et al.
CHEMBIOCHEM (2007)
Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate
Joseph A. Reddy et al.
CANCER RESEARCH (2007)
Combinatorial biosynthesis for drug development
Hugo G. Menzella et al.
CURRENT OPINION IN MICROBIOLOGY (2007)
Mutasynthesis - uniting chemistry and genetics for drug discovery
Kira J. Weissman
TRENDS IN BIOTECHNOLOGY (2007)
Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering
Andreas Kirschning et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2007)
Enzymatic release and macrolactonization of cryptophycins from a safety-catch solid support
Wolfgang Seufert et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Substrate specificity of strictosidine synthase
E McCoy et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly
Ian R. Baxendale et al.
CHEMICAL COMMUNICATIONS (2006)
Total synthesis and antitumor activity of ZK-EPO: The first fully synthetic epothilone in clinical development
Ulrich Klar et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from Nostoc cyanobionts
Nathan A. Magarvey et al.
ACS CHEMICAL BIOLOGY (2006)
Combinatorial biosynthesis of reduced polyketides
KJ Weissman et al.
NATURE REVIEWS MICROBIOLOGY (2005)
Chemoenzymatic synthesis of cryptophycin/arenastatin natural products
ZQ Beck et al.
BIOCHEMISTRY (2005)
Mutational biosynthesis -: a tool for the generation of structural diversity in the biosynthesis of antibiotics
S Weist et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition
K Patel et al.
CHEMISTRY & BIOLOGY (2004)
The biosynthesis of glycopeptide antibiotics - a model for complex, non-ribosomally synthesized, peptidic secondary metabolites
RD Sussmuth et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2004)
Mutasynthesis of glycopeptide antibiotics:: Variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine
S Weist et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum
P Spiteller et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Overview: Translating Hsp90 Biology into Hsp90 Drugs
Paul Workman
CURRENT CANCER DRUG TARGETS (2003)
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum
TW Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B
C Cuevas et al.
ORGANIC LETTERS (2000)
分享论文
