期刊
JOURNAL OF BIOSCIENCES
卷 32, 期 2, 页码 299-307出版社
INDIAN ACAD SCIENCES
DOI: 10.1007/s12038-007-0030-3
关键词
Withania somnifera; proteoglyean; collagenase; chondroprotection
类别
This is the first report describing two novel chondroprotective activities of aqueous extracts of Withania somnifera root powder. First, these extracts had a statistically significant, short-term chondroprotective effect on damaged human osteoarthritic cartilage matrix in 50% of the patients tested. Second, these extracts caused a significant and reproducible inhibition of the gelatinase activity of collagenase type 2 enzyme in vitro.
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