期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
卷 80A, 期 3, 页码 687-692出版社
WILEY
DOI: 10.1002/jbm.a.30891
关键词
bioactivity; electrochemical deposition; hydroxyapatite
A novel porous nano hydroxyapatite (HA) coating has been prepared on commercially pure titanium substrate by a modified electrochemical deposition method. The physico-chemical and biological properties of the coating were characterized by SEM, XRD, FTIR, Raman, and in vitro cell culture test respectively. The SEM patterns show a uniform microporous morphology consisting of wirelike crystals at nanometer scale. It is suggested that under controlled deposition conditions, the primary HA nanowires grow and self-assemble to construct an ordered microporous nest-like morphology, thus to form a nanomicro two-level Structure. The XRD results demonstrate that the HA nanowires are orderly arranged with their c-axis preferentially perpendicular to the substrate surface. The Raman and IR spectra affirm that the main component of the coating is well crystallized HA. An interdigitation phenomenon of the MG63 human osteosarcoma cells with the HA nanowires is observed in the hi vitro test, indicating excellent biocompatibility and bioactivity for the prepared coating. (c) 2006 Wiley Periodicals, Inc.
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