期刊
AUTOIMMUNITY
卷 40, 期 2, 页码 83-94出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08916930600911519
关键词
laminin; extracellular matrix; basal lamina; systemic lupus erythematosus; Sjogren's syndrom
类别
The extracellular matrix plays an important role in modulating the behavior of cells with which it interacts. There are a number of families of extracellular matrix (ECM) proteins including collagens, proteoglycans and laminins (LM). LM are the major component of the basal lamina (BL). Here, we review the current knowledge on their structure, self-assembly, binding mechanisms, diverse tissue-expression patterns and its impact on pathology. Studies and hypothesis exploring the role of LM and their polymorphic genes on autoimmune diseases (AIDs) such as systemic lupus erythematosus and Sjogren's syndrome (SS) are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据