期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 22, 期 3, 页码 394-402出版社
WILEY
DOI: 10.1359/JBMR.061118
关键词
Lrp5 knockout; PTH; histomorphometry; mu CT
Lrp5 deficiency decreases bone formation and results in low bone mass. This study evaluated the bone anabolic response to intermittent PTH treatment in Lrp5-deficient mice. Our results indicate that Lrp5 is not essential for the stimulatory effect of PTH on cancellous and cortical bone formation.
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