期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 387, 期 5, 页码 1613-1619出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-006-0856-9
关键词
repeatability; reproducibility; variance components; dental caries; optical coherence tomography; Raman spectroscopy
资金
- NIDCR NIH HHS [R01 DE017889-01] Funding Source: Medline
The demineralization of enamel that is associated with early caries formation affects the optical properties of the enamel. Polarized Raman spectroscopy and optical coherence tomography have been used to detect these changes and potentially offer a means to detect and monitor early caries development. The total optical attenuation coefficient as measured by optical coherence tomography and the polarization anisotropy of the Raman peak arising from the symmetric v(1) vibration of PO43- 4 at approximately 959 cm(-1) have been demonstrated as being sensitive markers of early caries. This ex vivo study on extracted human teeth demonstrates that these measurements can be made with reasonable precision with concomitantly good repeatability and reproducibility in sound enamel. Such reliability is crucial for these techniques to have a practical clinical value.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据