Solvent-free microwave-assisted conversion of Baylis-Hillman adducts of ninhydrin into functionalized spiropyrrolidines/pyrrolizidines through 1,3-dipolar cycloaddition

Microwave-assisted synthesis of spiropyrrolidines/pyrrolizidines has been accomplished using the alkene unit of Baylis-Hillman adducts of ninhydrin with sarcosine/proline and various activated ketones through 1,3-dipolar cycloaddition. (c) 2007 Published by Elsevier Ltd.