期刊
FEBS LETTERS
卷 581, 期 5, 页码 981-988出版社
WILEY
DOI: 10.1016/j.febslet.2007.01.081
关键词
microRNA; bovine; adipose; mammary gland; rumen
We report the identification of bovine miRNAs by cloning small RNAs from adipose tissue and the mammary gland. Fifty-nine distinct miRNAs were identified, five of them were not homologous to known mammalian miRNAs, and many of them had 3' and/or 5' end variants. Ribonuclease protection assays indicated that miR-23a and miR-24, whose genes are closely located on the same chromosome, were co-expressed in different tissues. The assays also suggested a role for several miRNAs in the mammary gland and a role for miR-133, a previously known skeletal and cardiac muscle-specific miRNA, in the rumen, an organ unique to the ruminant. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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