期刊
FEBS LETTERS
卷 581, 期 5, 页码 1041-1046出版社
WILEY
DOI: 10.1016/j.febslet.2007.02.007
关键词
recessive resistance; eIF4E; eIF4G; plant potyvirus
The translation initiation factors eIF4E and eIF (iso)4E play a key role during virus infection in plants. During mRNA translation, eIF4E provides the cap-binding function and is associated with the protein eIF4G to form the eIF4F complex. Susceptibility analyses of Arabidopsis mutants knocked-out for At-eIF4G genes showed that eIF4G factors are indispensable for potyvirus infection. The colonization pattern by a viral recombinant carrying GFP indicated that eIF4G is involved at a very early infection step. Like eIF4E, eIF4G isoforms are selectively recruited for infection. Moreover, the eIF4G selective involvement parallels eIF4E recruitment. This is the first report of a coordinated and selective recruitment of eIF4E and eIF4G factors, suggesting the whole eIF4F recruitment. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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