期刊
JOURNAL OF NEUROSCIENCE
卷 27, 期 10, 页码 2663-2672出版社
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.4844-06.2007
关键词
auditory cortex; evoked magnetic fields; gamma band; plasticity; learning; time; MEG; synchronization
资金
- NIDCD NIH HHS [R01 DC004855, R01 DC004855-01A1] Funding Source: Medline
The discrimination of temporal information in acoustic inputs is a crucial aspect of auditory perception, yet very few studies have focused on auditory perceptual learning of timing properties and associated plasticity in adult auditory cortex. Here, we trained participants on a temporal discrimination task. The main task used a base stimulus (four tones separated by intervals of 200 ms) that had to be distinguished from a target stimulus (four tones with intervals down to similar to 180 ms). We show that participants' auditory temporal sensitivity improves with a short amount of training (3 d, 1 h/d). Learning to discriminate temporal modulation rates was accompanied by a systematic amplitude increase of the early auditory evoked responses to trained stimuli, as measured by magnetoencephalography. Additionally, learning and auditory cortex plasticity partially generalized to interval discrimination but not to frequency discrimination. Auditory cortex plasticity associated with short-term perceptual learning was manifested as an enhancement of auditory cortical responses to trained acoustic features only in the trained task. Plasticity was also manifested as induced non-phase-locked high gamma-band power increases in inferior frontal cortex during performance in the trained task. Functional plasticity in auditory cortex is here interpreted as the product of bottom-up and top-down modulations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据