Selectively coated photonic crystal fiber for highly sensitive fluorescence detection

The authors investigate the potential of hollow core photonic crystal fibers (HCPCFs) for highly sensitive fluorescence detection by selectively coating the central hole of a HCPCF with fluorophores. After studying the influence of reabsorption and intermolecular effects on the emission, they show that dye concentrations down to 10(-9)M can be detected using only nanoliter sample volumes. The results indicate that HCPCF are well suited for sensing applications involving internal emission or scattering processes, such as fluorescence based gas sensing or surface-enhanced Raman scattering, and may be integrated into compact optical devices. (c) 2007 American Institute of Physics.