期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 129, 期 10, 页码 2766-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja068919r
关键词
-
资金
- NIGMS NIH HHS [R01 GM049093-14, R01 GM049093-15, R01 GM049093-13, GM-49093, R01 GM049093] Funding Source: Medline
The regiochemistry of the intramolecular Schmidt reaction of 2-substituted ketones has proved susceptible to control by the placement of an aromatic group at an adjacent position, permitting the selective formation of a series of bridged bicyclic lactams from these substrates. This phenomenon is ascribed to the presence of stabilizing through-space interactions between the positively charged leaving group and the aromatic substituents in a key azidohydrin intermediate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据