期刊
TALANTA
卷 71, 期 4, 页码 1675-1678出版社
ELSEVIER
DOI: 10.1016/j.talanta.2006.07.048
关键词
DNA; damage; quantum dots; nucleic acid molecular light switches
The calf thymus DNA (ctDNA) damage induced by water-soluble CdSe quantum dots (QDs) was investigated using nucleic acid molecular light switches as probe. It was found that little ctDNA was damaged by CdSe QDs without UV irradiation. However, under UV irradiation, ctDNA was nicked by CdSe QDs very clearly. The mechanism of ctDNA damage was also discussed. The results strongly suggested that the ctDNA damage caused by CdSe QDs was not due to photo-induced liberation of Cd2+, but due to the production of free radicals and reactive oxygen species. (c) 2006 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据